Faculty Research

• Division of Regional Anesthesia : Director: Edward R. Mariano, M.D..
  
  
• Hastings Research Lab: Director: Randolph H. Hastings, M.D., Ph.D.  Ongoing work in parathyroid hormone-related protein (PTHrP) and lung biology, cellular mechanisms of alveolar protein clearance, mechanics of laryngoscopy and airway management of cervical spine injured patients. .

• Roth Research Lab:  Director David M. Roth Ph.D., M.D.  Ongoing work in the molecular mechanisms of anesthetic induced cardiac protection, myocardial ischemia, cardiac hypertrophy, remodeling and congestive heart failure.

• Center for Clinical Pain Research : Director: Mark S. Wallace, M.D.

• Anesthesia Ergonomics Lab : Director: Steve Chang, M.D.

• Neuro Anesthesia Research Lab : Piyush Patel, M.D. FRCPC, John C Drummond, MD. FRCPC
  I schemic preconditioning is a phenomenon by which minor non-injurious stresses to the brain render the brain less vulnerable to subsequent ischemic injury.  Using a comprehensive strategy that includes microarray analysis of gene transcription and proteomics, the goal is to identify candidate genes that might mediate ischemic preconditioning.
  Regeneration of regions of the brain that are damaged by ischemic insults can be accomplished by the transplantation of stem cells.  Embryonic and adult stem cells are harvested, labeled and transplanted into the post-ischemic brain.  The goal is to identify the optimum conditions for survival and growth of the transplanted cells, characterization of the synaptic connections that develop between transplanted cells and native cells and the determination of the impact of stem cell transplantation on neurocognitive function

• Edward Mariano, M.D. and Brian Ilfeld, M.D., M.S.
• Effect of infraorbital nerve blocks on immediate and long-term recovery following outpatient nasal surgery
• Optimizing local anesthetic concentration for continuous peripheral nerve block local anesthetic infusions (multi-center)
• Optimizing perineural catheter location for continuous brachial plexus nerve block local anesthetic infusions
• Continuous femoral nerve blocks following total knee arthroplasty and their effects on readiness-for-discharge (multi-center)
• Continuous psoas compartment nerve blocks following total hip arthroplasty and their effects on readiness-for-discharge (multi-center)
• The fiscal effects of providing continuous peripheral nerve blocks on an ambulatory basis